Review Article

Hyperthermia: A Neoadjuvant Therapeutic Approach in Cancer Treatment

Fahimeh Faghihi Moghadam, Mohsen Bakhshandeh , Hüseyin Sahinbas

Fahimeh Faghihi Moghadam
Department of Medical Physics, Faculty of Medical Sciences ,Shahid Beheshti University of Medical Science, Tehran ,Iran

Mohsen Bakhshandeh
Department of Radiology, Faculty of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Email:

Hüseyin Sahinbas
Institute for hyperthermia Research, Partner of the Marien Hospital Herne, Hospital of the Ruhr-University , Bochum-Germany
Online First: March 29, 2017 | Cite this Article
Faghihi Moghadam, F., Bakhshandeh, M., Sahinbas, H. 2017. Hyperthermia: A Neoadjuvant Therapeutic Approach in Cancer Treatment. The Cancer Press 3(1): 1-5. DOI:10.15562/tcp.35

Hyperthermia refers to elevation tumor temperature from 39 up to 43 degree Celsius. Actually Therapeutic Hyperthermia has been used as an adjuvant treatment for cancer, since end of the 19th century after observations William Coley who found that tumor is diminished after induction of fever by bacterial toxins. Hyperthermia therapy refers to treatment tumors through heating which has been used since the time of the ancient Egyptians. The term ‘Hyperthermia’ in oncology means treatment of malignant disease by heating in different ways. Hyperthermia is usually applied as an adjuvant therapy method in combination with other modalities such as Radiotherapy or Chemotherapy in cancer treatment. Typically there are three categories for Hyperthermia, including local, regional and whole body. Based on the temperature Whole body hyperthermia classify in 3 type, mild, fever range and extreme. In Mild hyperthermia, the temperature is from 37.5 up to 38.5 degree Celsius, in fever range hyperthermia, 38.5 up to 40 degree Celsius, and extreme hyperthermia, the temperature above 40 degree Celsius. Now Days Whole body hyperthermia known as immunotherapy related to cancer treatment in oncology. Here we will review whole body hyperthermia related to cancer treatment.



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